During the fifth inning of Game Two at Toronto’s Rogers Centre on Saturday, October 25, 2025, the scheduled Stand Up To Cancer tribute paused play as players, broadcasters and fans honored loved ones affected by cancer. Many viewers anticipated the game to resume immediately after the tribute — but the evening took an unexpected turn when the Jonas Brothers began a brief on-field performance.

The trio performed “I Can’t Lose,” a track from their 2025 album Greetings From Your Hometown. The surprise set — which followed the tribute — prompted swift reaction on social platforms, with numerous viewers calling the timing jarring or ill-suited to a live pitcher’s duel.

On X, one user quipped that “if the Jays lose it’s entirely on that weird Jonas Brothers performance,” while others expressed bemusement at what they described as a concert-like interruption midgame. Several fans joked the short break altered momentum, noting the Dodgers went on to win 5–1.

Some responses leaned humorous: one commenter playfully credited the Brothers for helping the Dodgers’ comeback, and another lamented that seeing a pop set amid the World Series wasn’t something they’d expected to encounter on their viewing bingo cards.

The Jonas Brothers are official ambassadors for Stand Up To Cancer and had previously expressed appreciation for being included in the ceremony. Representing a partnership with Mastercard to support the campaign, the band said they were honored to join a moment that combined music with a charitable cause and to perform at a major baseball moment they personally value as long-time fans.

MLB’s opening game also featured a musical component: Pharrell Williams and the Voices of Fire choir delivered a two-song set from their Ophaním project and performed both the U.S. and Canadian national anthems before the first pitch.

Watch the Jonas Brothers’ World Series performance on YouTube: youtu.be/dUgcvr4yTxI