George Clooney has voiced interest in reuniting with his ER co-star Noah Wyle on the new medical procedural Pitt Hospital. Speaking at HBO’s project presentation in New York, studio chief Casey Bloys said he would welcome the opportunity to see the actors together again, calling Clooney a desirable guest for the series.
That said, there have been no formal discussions about Clooney joining the cast so far. Still, could we see him pop up in a potential third season of Pitt Hospital? The second season is slated to premiere in January 2026.
For context, George Clooney and Noah Wyle were both nominated for Emmy and Golden Globe awards for their work on the series ER.

