Tooth sensitivity with a desensitizing-containing at-home bleaching gel-a randomized triple-blind clinical trial

J Dent. 2018 May:72:64-70. doi: 10.1016/j.jdent.2018.03.006. Epub 2018 Mar 15.

Abstract

Objectives: Desensitizing agents are usually included in the composition of bleaching agents to reduce bleaching-induced tooth sensitivity (TS). This randomized clinical trial (RCT) evaluated the risk and intensity of TS and color change after at-home bleaching with a desensitizing-containing (3% potassium nitrate and 0.2% sodium fluoride) and desensitizing-free 10% carbamide peroxide (CP) gel (Whiteness Perfect, FGM).

Methods: A triple-blind, within-person RCT was conducted on 60 caries-free adult patients. Each participant used the gel in a bleaching tray for 3 h daily for 21 days in both the upper and lower dental arches. The absolute risk and intensity of TS were assessed daily through the 0-10 VAS and NRS scale for 21 days. Color change was recorded using shade guides (Vita Classical and Vita Bleachedguide) and the Easyshade spectrophotometer at baseline, weekly and 30 days after the end of the bleaching. The risk and intensity of TS were evaluated by the McNemar and Wilcoxon Signed Rank tests, respectively. Color change (ΔSGU and ΔE) were evaluated by the Mann-Whitney test and a paired t-test, respectively (α = 0.05).

Results: No difference in the TS and color change was observed (p > 0.05).

Conclusions: The incorporation of potassium nitrate and sodium fluoride in 10% carbamide peroxide at-home bleaching gel tested in this study did not reduce the TS and did not affect color change (RBR-4M6YR2).

Keywords: Dentin sensitivity; Desensitizing agents; Tooth bleaching agents.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Adult
  • Carbamide Peroxide / adverse effects
  • Color
  • Dentin Desensitizing Agents / therapeutic use*
  • Dentin Sensitivity / etiology
  • Dentin Sensitivity / prevention & control*
  • Female
  • Humans
  • Hydrogen Peroxide / adverse effects
  • Male
  • Middle Aged
  • Nitrates / therapeutic use
  • Potassium Compounds / therapeutic use
  • Sodium Fluoride / therapeutic use
  • Spectrophotometry
  • Tooth Bleaching / adverse effects*
  • Tooth Bleaching / methods
  • Tooth Bleaching Agents / adverse effects*
  • Tooth Discoloration
  • Young Adult

Substances

  • Dentin Desensitizing Agents
  • Nitrates
  • Potassium Compounds
  • Tooth Bleaching Agents
  • Carbamide Peroxide
  • Sodium Fluoride
  • Hydrogen Peroxide
  • potassium nitrate