The Effect of Prefrontal Transcranial Direct Current Stimulation on Attention Network Function in Healthy Volunteers

Neuromodulation. 2018 Jun;21(4):355-361. doi: 10.1111/ner.12629. Epub 2017 Jul 17.

Abstract

Objectives: The effect of acute transcranial direct current stimulation (tDCS) on cortical attention networks remains unclear. We examined the effect of 20 min of 2 mA dorsolateral prefrontal cortex tDCS (bipolar balanced montage) on the efficiency of alerting, orienting and executive attention networks measured by the attention network test.

Materials and methods: A between-subjects stratified randomized design compared active tDCS vs. sham tDCS on attention network function in healthy young adults.

Results: Executive attention was greater following active vs. sham stimulation (d = 0.76) in the absence of effects on alerting, orienting, or global RT or error rates. Group differences were not moderated by state-mood.

Conclusion(s): Twenty minutes of active 2 mA tDCS over left DLPFC is associated with greater executive attention in healthy humans.

Keywords: Attention network test; attention control; executive control; transcranial direct current stimulation.

MeSH terms

  • Adolescent
  • Affect / physiology
  • Analysis of Variance
  • Anxiety / physiopathology
  • Attention / physiology*
  • Blood Pressure / physiology
  • Brain Mapping*
  • Female
  • Healthy Volunteers
  • Heart Rate / physiology
  • Humans
  • Male
  • Neural Pathways / physiology*
  • Pain Measurement
  • Prefrontal Cortex / physiology*
  • Random Allocation
  • Reaction Time / physiology
  • Transcranial Direct Current Stimulation / methods*
  • Young Adult