[HTML][HTML] The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens
Background A sequenced house dust mite (HDM) genome would advance our
understanding of HDM allergens, a common cause of human allergies. Objective We sought
to produce an annotated Dermatophagoides farinae draft genome and develop a combined
genomic-transcriptomic-proteomic approach for elucidation of HDM allergens. Methods AD
farinae draft genome and transcriptome were assembled with high-throughput sequencing,
accommodating microbiome sequences. The allergen gene structures were validated by …
understanding of HDM allergens, a common cause of human allergies. Objective We sought
to produce an annotated Dermatophagoides farinae draft genome and develop a combined
genomic-transcriptomic-proteomic approach for elucidation of HDM allergens. Methods AD
farinae draft genome and transcriptome were assembled with high-throughput sequencing,
accommodating microbiome sequences. The allergen gene structures were validated by …