Sarcoptes scabiei: histopathological changes associated with acquisition and expression of host immunity to scabies
LG Arlian, CM Rapp, DL Vyszenskimoher… - Experimental …, 1994 - Elsevier
The sequential changes in the histology in scabietic lesions were investigated for hosts
(rabbits) during sensitization and reinfestation with Sarcoptes scabiei. Experimentally
infested naive hosts developed heavy scabies infestations but 65% of the hosts showed
induced immunity (resistance) to reinfestation. All hosts (naive, immune, and susceptible)
exhibited an initial cell infiltrate in scabietic lesions that consisted predominantly of
neutrophils and a few macrophages. This was followed by a dense plasma cell infiltrate …
(rabbits) during sensitization and reinfestation with Sarcoptes scabiei. Experimentally
infested naive hosts developed heavy scabies infestations but 65% of the hosts showed
induced immunity (resistance) to reinfestation. All hosts (naive, immune, and susceptible)
exhibited an initial cell infiltrate in scabietic lesions that consisted predominantly of
neutrophils and a few macrophages. This was followed by a dense plasma cell infiltrate …