Clinical Picture and Antibody Response in Pigs Infected by Sarcoptes scabiei var, suis

SET BORNSTEIN, G ZAKRISSON - Veterinary Dermatology, 1993 - Wiley Online Library
SET BORNSTEIN, G ZAKRISSON
Veterinary Dermatology, 1993Wiley Online Library
Clinical signs and antibody responses were observed in juvenile SPF‐pigs experimentally
infected with Sarcoptes scabiei var. suis and in neonatal pigs born to a sow cronically
infected with S. scabiei. Mange became evident after 2–3 weeks. Three SPF‐pigs, which
were infected twice, developed clinical signs a few days earlier than three other SPF‐pigs
infected once. Serum antibodies to S. scabiei were demonstrated by an ELISA, using an
extract of S. scabiei var. vulpes as an antigen, 5–7 weeks after the experimental infection …
Abstract
Clinical signs and antibody responses were observed in juvenile SPF‐pigs experimentally infected with Sarcoptes scabiei var. suis and in neonatal pigs born to a sow cronically infected with S. scabiei. Mange became evident after 2–3 weeks. Three SPF‐pigs, which were infected twice, developed clinical signs a few days earlier than three other SPF‐pigs infected once. Serum antibodies to S. scabiei were demonstrated by an ELISA, using an extract of S. scabiei var. vulpes as an antigen, 5–7 weeks after the experimental infection and significant levels of antibody to S. scabiei were seen during the acute and chronic phases of the disease. Pruritus was seen at 4 days of age in piglets born to the infected sow. Maternal antibodies to S. scabiei were demonstrated within 6 h reaching mean maximum levels between 24 and 48 h after birth.
Résumé— Les symptômes et la réponse anticorps chez des pores SPF infestés expérimentalement par Sarcoptes scabiei var. suis et des porcelets nouveaux nés dans une porcherie infectée chroniquement par Sarcoptes scabiei one étéétudiés. La gale est apparue au bout de deux à trois semaines. Trois pores SPF, qui ont été infectés deux fois, ont présenté des symptômes quelques jours avant trois porcelet SPF infectés une seule fois. Les anticorps spécifiques de Sarcoptes scabiei ont été mis en évidence par une technique EIA, utilisant comme antigène des extraits de Sarcoptes scabiei tar. vulpes, 5 à 7 semaines après l'inoculmation. Des taux significatifs ont été observés tant pendant la phase aigue aue la phase chronique de la maladie. Le prurit était observé dès l'âge de 4 jours pour les porcelets nés dans la porcherie infectée. Des anticorps maternels spécifiques Sarcoptes scabiei ont été mis en evidence dès la sixième heure, avec des pics maximum entre 24 et 48 heures après la mise‐bas.
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