A diagnostic test for scabies: IgE specificity for a recombinant allergen of Sarcoptes scabiei

R Jayaraj, B Hales, L Viberg, S Pizzuto, D Holt… - … and infectious disease, 2011 - Elsevier
Scabies infestations are difficult to diagnose clinically and current serologic tests have less
than 50% accuracy. To develop more reliable diagnosis of scabies, specific IgE antibodies
to a major scabies antigen recombinant Sar s 14.3 (rSar s 14.3) were measured in 140
plasma samples from scabies-infested and control subject groups using dissociation-
enhanced lanthanide fluorescent immunoassays (DELFIA). Levels of rSar s 14.3-specific IgE
were quantified, and cross-reactivity with its house dust mite homologue, Der p 14, was …